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Conservative hypothesis tests and confidence intervals using importance sampling

Matthew T. Harrison

Biometrika · 2012 · Volume 99 · Issue 1

DOI: 10.1093/biomet/asr079

Abstract

Importance sampling is a common technique for Monte Carlo approximation, including that of p -values. Here it is shown that a simple correction of the usual importance sampling p -values provides valid p -values, meaning that a hypothesis test created by rejecting the null hypothesis when the p -value is at most α will also have a Type I error rate of at most α . This correction uses the importance weight of the original observation, which gives valuable diagnostic information under the null hypothesis. Using the corrected p -values can be crucial for multiple testing and also in problems where evaluating the accuracy of importance sampling approximations is difficult. Inverting the corrected p -values provides a useful way to create Monte Carlo confidence intervals that maintain the nominal significance level and use only a single Monte Carlo sample.

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