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Tweedie’s Formula and Selection Bias

Bradley Efron

Journal of the American Statistical Association · 2011 · Volume 106 · Issue 496

DOI: 10.1198/jasa.2011.tm11181

Abstract

We suppose that the statistician observes some large number of estimates z i , each with its own unobserved expectation parameter μ i . The largest few of the z i ’s are likely to substantially overestimate their corresponding μ i ’s, this being an example of selection bias , or regression to the mean. Tweedie’s formula, first reported by Robbins in 1956, offers a simple empirical Bayes approach for correcting selection bias. This article investigates its merits and limitations. In addition to the methodology, Tweedie’s formula raises more general questions concerning empirical Bayes theory, discussed here as “relevance” and “empirical Bayes information.” There is a close connection between applications of the formula and James–Stein estimation.

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